TRYPTIC ACTIVATION OF ACETYLATED CHYMOTRYPSINOGEN
نویسندگان
چکیده
منابع مشابه
The lodination of Chymotrypsinogen
Katz, E. & Weissbach, H. (1963). J. biol. Chem. 238, 666. Kossel, A. & Edlbacher, S. (1915). Hoppe-Seyl. Z. 94, 264. Linko, P., Alfthan, M., Miettinen, J. K. & Virtanen, A. I. (1953). Acta chem. 8cand. 7, 1310. Lowry, 0. H., Rosebrough, N. J., Farr, A. L. & Randall, R. J. (1951). J. biol. Chem. 193, 265. Moore, S. & Stein, W. H. (1948). J. biol. Chem. 176, 367. Ratner, S., Nocito, V. & Green, D...
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Gerwing, Julia (University of British Columbia, Vancouver, B.C., Canada), Claude E. Dolman, and Arthur Ko. Mechanism of tryptic activation of Clostridium botulinum type E toxin. J. Bacteriol. 89:1176-1179. 1965.-The toxic peptide of trypsin activated Clostridium botulinum type E toxin was purified by chromatography through columns packed with Sephadex G-75 and G-50. The molecular weight of the ...
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Procarboxypeptidases are the remaining major digestive zymogens the activation process of which remains unsolved. Here it is shown that in the tryptic activation of monomeric procarboxypeptidase A from porcine pancreas, the generation of carboxypeptidase A (CPA) activity parallels the limited proteolysis of the 94-residue activation segment. This degradation proceeds from the COOH-terminal end ...
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متن کاملAmino terminal group in chymotrypsinogen.
Bovine chymotrypsinogen Q! was examined for N-terminal groups by Rovery et al. (l), using both the dinitrophenyl (DNP) and the phenyl isocyanate techniques (2, 3). Their failure to find evidence for any such group, together with the absence of a C-terminal residue reactive towards carboxypeptidase (4), suggested that this protein consists of one or more cyclic peptide chains. Evidence has now b...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1964
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.51.2.151